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Description
The glucagon-like peptide 1 receptor agonist Exendin-4 decreases relapse-like drinking in socially housed mice
A randomized, double-blind, placebo-controlled, parallel-group study showed that among the patients with T2DM treated with EX monotherapy, EX could improve glycated hemoglobin, fasting blood glucose, and postprandial blood glucose control, reduce weight, improve cell function, and adjust blood pressure
include sitagliptin (Januvia), which was approved in 2006, followed by saxagliptin (Onglyza) in 2009, linagliptin (Tradjenta) in 2011, and alogliptin (Nesina) in 2013
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At 68 weeks, 14.1% of participants in the 9mg group reported being completely pain-free, compared to 4.2% on placebo
