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Methods We conducted a single-center observational cohort study that included adult patients with IBD who were started on GLP-1-based therapy (semaglutide or tirzepatide) for weight loss from January 2021 to April 2024

Long-term corticosteroid usestandard therapy for moderate-to-severe lupuscauses centralized weight gain, increased appetite, and metabolic dysfunction independent of caloric intake

Medical relevance of common protein-altering variants in GPCR genes across 337,205 individuals in the UK Biobank

Documented evidence, such as a diagnosis from a doctor or an A1C result of 6.5 or above, is required for a prescription