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Drugging this type of GPCR with small molecules has its challenges say Jeff Finer, chief executive of Septerna, a biotech based in south San Francisco, US

In: Office of disease prevention and health promotion USDoHaHS, ed

Men who are overweight or have type 2 diabetes may experience stress, low self-esteem, and depression

In addition, no increase in cardiovascular outcomes were observed in SUSTAIN 6 and PIONEER 6, which is reassuring given the initial fear of adverse cardiac events with increased resting heart rates

Am J Physiol Endocrinol Metab (2017) 313(6):E651e62