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The optimal ratio in receptor potency has yet to be found to optimize clinical benefits without imposing additional safety issues [29]

However, the principle of GLP-1 regulating BP is still not fully understood

examined 224 IBD patients on GLP-1 receptor agonists and found no significant change ( p = 0.36) in the rates of IBD exacerbation (measured as a composite of IBD-related hospitalizations, steroid prescriptions, medication escalation or adjustments, or IBD-related surgeries) after 12 months of GLP-1 RA therapy, compared to the 12 months prior to treatment [36]

friction may cause it to detach or the needles to break

The GLP-1 and hair loss guide explains the mechanism, timeline, and strategies for minimizing this side effect