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Activation of GLP-1R also enhances the levels of anti-inflammatory cytokines like IL-4 and IL-10, along with increasing the expression of the neuroprotective factor -endorphin in microglia [112]

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Specifically, tezepatide can reduce TC, LDL-C and TG levels by 12.9%, 15.5%, and 24.9%, respectively, and increase HDL-C levels by 0.9% [128]
