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Diabetes Care 14 , 914918 (1991)

As little as 3 percent weight loss can have a meaningful benefit for diabetes, hyperglycemia and dyslipidemia (abnormal lipid levels in the bloodstream, which poses a higher risk for cardiovascular disease)but these conditions, along with many others, often require a greater amount of weight loss to lead to health improvements

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However, the risk of hypoglycemia (dangerously low blood sugar) increases when semaglutide is paired with insulin or sulfonylureas