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Using biologics such as enzymes, manufacturers may be able to assemble peptide chains in a water-based environmentan approach that could unlock multiple benefits: Less dependence on hazardous chemicals: By shifting away from a chemical-heavy solid-phase synthesis approach, manufacturers could free themselves from the costs and complexities of sourcing, storing, handling, and disposing of hazardous raw materials

Food and Drug Administration placed a box warning on GLP-1 medications due to this risk in rodents

Approval of tirzepatide for apnea was given on the basis of a study that showed the drug reduced the condition by up to 62.8 percent

Yi et al., 2024)