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Budesonide MMX may be considered for some patients

Accessibility & Patient Preference Many patients have avoided GLP-1 treatments due to fear of injections or practical concerns with weekly administration (vs
345,346 GLP-1 may also reduce the expression of cartilage-degrading enzymes by inhibiting the MAPK pathway or activating anti-inflammatory pathways such as PI3K/Akt, thereby alleviating cartilage damage

Tirzepatide: A dual GIP/GLP-1 receptor agonist - a new antidiabetic drug with potential metabolic activity in the treatment of type 2 diabetes