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BPC 157 is a synthetic peptide made of 15 amino acids and is derived from a protective protein naturally found in the stomach

The anorectic and thermogenic effects of estradiol can be direct, through genomic and non-genomic mechanisms, or indirect, through activation of peripheral mediators such as cholecystokinin (CCK), insulin, leptin and GLP-1

Blood sugar is also tracked, particularly in patients who have diabetes alongside obesity

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however, because this was a retrospective target trial emulation with a relatively small number of events, it is not yet practice-changing and should instead be viewed as a signal that supports further research into the role of GLP-1 receptor agonists in epileptogenesis. Limitations and future directions The authors emphasised that the study design was observational, despite using advanced statistical methods to emulate a clinical trial