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doi: 10.3390/ijerph191911852

Treatment groups were compared with an ad libitum vehiclefed group and a weight-matched control group, to differentiate between the effects of weight loss induced by food restriction and GLP-1RA treatment (Supplemental Figure 10A)

They come in small volumes (0.3, 0.5, 1.0 mL) marked 30, 50, or 100 insulin units
With the GLP-1 receptor there is the pathway linked to insulin control, but also a pathway that recruits the signalling molecule beta arrestin, which causes the side effects but also results in the whole receptor and drug molecule being taken inside the cell, shutting down any further activity

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