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what is tirzepatide vs semaglutide vs. Semaglutide: What's the Difference? Tirzepatide vs Semaglutide: 2026 Clinical
Description
Yes, you can become pregnant while taking GLP-1 medications like semaglutide, but current evidence recommends discontinuing these medications before attempting conception

Fitchett D, Zinman B, Wanner C, Lachin JM, Hantel S, Salsali A, et al

Choose the Best Medication Plan GLP-1s (like semaglutide or tirzepatide injectable or oral), phentermine, or a combination

In vivo evidence of the role of GLP-1/GLP-1R is from Glp-1r / mice, which exhibited an increased number of osteoclasts accompanied by greater bone resorption activity and increased expression of osteoclast-related genes

The pill and injection had similar tolerability in clinical trials
