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The main concerns are dehydration, nausea, meal quality, glucose changes, and how other medicines interact with long fasting hours

The Side Effect Timeline Most Retatrutide users follow a predictable pattern: Weeks 1-3: Mild symptoms begin
The injection site (stomach, thigh, or arm) does not change the optimal time of day for your dose

10.1016/j.cmet.2016.08.020 98

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