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Short-term semaglutide use can produce meaningful weight loss, but research suggests sustained therapy often works better for maintaining results

In particular, incretin-based therapies and sodium-glucose co-transporter 2 (SGLT2) inhibitors have attracted increasing interest not only for their glucose-lowering effects, but also for their broader metabolic, renal, and cardiovascular benefits

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Like any intervention, their use should be based on risk-benefit analysis, taking into consideration individual patient factors.

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