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Constipation affects many people taking GLP-1 medications like semaglutide

The GLP-1 NAION vision-loss MDL hit 146 cases on the July JPML report up 70% in two months as the GI-injury MDL heads to Rule 702 hearings September 10-18.

It increases intestinal glucose uptake and lactate production, increases GLP-1 concentrations and the bile acid pool within the intestine, and alters the microbiome

Obesity affects over 1.9 billion people worldwide.[1]In 2024, global spend on anti-obesity medication exceeded $30 billion for the first time, which is over a ten-fold increase since 2020, as reported by IQVIA.[2]This is driven by an unprecedented and ever-increasing demand for appetite-suppressing drugs, with Novo Nordisk being a leader in the research, development and manufacture []