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Terns Pharmaceuticals reports topline 12-week data from its phase 2 trial evaluating oral GLP-1 receptor agonist TERN-601 in obesity

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However, some key histone modifications, such as H3K4me3 and H3K27me3, are retained and can be transmitted to the next generation [189]

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That additional mechanism translated to roughly 28% average weight loss in TRIUMPH-1, approximately five to six percentage points higher than tirzepatide in comparable populations