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This review article examines the translational evolution of glucagon-like peptide-1 receptor agonists (GLP-1RAs), tracing their progression from the discovery of exendin-4 in Gila monster venom to long-acting peptide analogues and the first orally delivered peptide therapy, oral semaglutide

Metabolic bariatric procedures, such as sleeve gastrectomy, achieve rapid and clinically meaningful weight reduction, often resulting in improved operative exposure and technical conditions for subsequent resection