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Thus, in comparison with several oral antidiabetic drugs that are available for managing type II diabetes mellitus, including metformin, sulfonylureas, sodiumglucose cotransporter 2 (SGLT2) inhibitors, thiazolidinediones, alphaglucosidase inhibitors, and meglitinides [138, 139], the benefits of DPP4 inhibitors relative to other oral antidiabetic medications are summarized in Table 3
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Dopamine plays a prominent role in the immediate reinforcing/rewarding effects of drugsthe dopamine theory, and dysregulation of the dopamine system is thought to contribute to the addicted state as a predisposing factor and/or a consequence of chronic substance use (Volkow, Michaelides, et al., 2019)