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Without specific safety data on these formulations during breastfeeding, they should be avoided

doi: 10.1186/s40248-016-0066-z

Mechanically, it slows down stomach emptying which also makes you feel more full after a meal

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This pocket is formed by residues in transmembrane helices 1 (TM1), 2 (TM2), 3 (TM3), and 7 (TM7), along with contributions from extracellular loop 2 (ECL2)