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These covariates included demographics (age, gender [male, female, unknown], race [Black or African American, White, Asian], ethnicity [Hispanic or Latino, Not Hispanic or Latino, unknown], and marital status), socioeconomic determinants of health (SDOHs) including education, employment, environmental exposure, and housing, problems related to lifestyle, cancer, diabetes severity indicators (e.g., obesity, complications like nephropathy, liver, neuropathy, heart disease), some conditions known to be associated with constipation or intestinal obstruction (e.g., diseases of intestines, diseases of appendix), and prior prescription of medicines associated with diabetes, decreased intestinal motility, or constipation [15, 16, 27,28,29,30]

Collagen Protecting Your Skin During Rapid Weight Loss Why it matters: Significant or rapid weight loss, a hallmark of GLP-1 success, can outpace the skin's ability to retract, leading to loose or sagging skin

American Institute for Cancer Research

[12, 13] Taken together, these findings establish GLP-1 receptor agonists as among the most effective medical therapies for both diabetes and obesity, driving their rapid and widespread use

What Are GLP-1 Medications & How Do They Work