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Protocol phase 2: initiation (weeks 1 through 8) Week 1: Begin tirzepatide at 2.5mg

PubMed Objective: Although the pathogenesis of non-alcoholic fatty liver disease (NAFLD) has been extensively studied, the role of its underlying pathogenesis remains unclear, and there is currently no approved therapeutic strategy for NAFLD

Over several weeks, your provider will typically increase the dose in a stepwise fashion

It will often be prescribed with the intention of being a long-term medication if the patient responds well and is able to continue increasing the dosage until it is maximized

Making a determination regarding drug shortage status in a declaratory order issued as a product of informal adjudication is well within FDAs discretion under the FD&C Act and the APA, the letter stated