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Studies show that stopping too early (before reaching 1015% body weight loss) increases the risk of regaining 50% or more of lost weight within 12 years

[DOI] [PMC free article] [PubMed] [Google Scholar] 220.Neumann UH, et al

While GLP-1 medicines like semaglutide can last for about a week or so in the body, human GLP-1 has a half-life of only about two minutes 12

In a trial of 21 healthy seniors confined to bed rest for 10 days, it was well-tolerated and demonstrated an ability to reduce muscle atrophy compared to a placebo

These health problems can already affect hormone balance
