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Using this therapy as a tool to treat PAD in patients without diabetes may be a game-changer in terms of reducing morbidity and mortality. Prospective controlled clinical trials are warranted to examine the current impact of GLP-1RA on non-diabetic PAD patients

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While it may produce somewhat less weight loss than injectable semaglutide or tirzepatide, it represents a scientifically validated needle-free option

10.1038/s41598-018-30457-y [DOI] [PMC free article] [PubMed] [Google Scholar] 37.Bril, F