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[1] [2] This triple-receptor mechanism distinguishes it from currently approved agents such as semaglutide (a GLP-1 agonist) or tirzepatide (a dual GIP/GLP-1 agonist)

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Glucagon-like peptide 1 and glucose-dependent insulinotropic polypeptide stimulate release of substance P from TRPV1- and TRPA1-expressing sensory nerves

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Ez megzavarja az L-sejtek mkdst, cskkenti a GLP-1 felszabadulst, s rossz glkz-anyagcserhez vezet

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