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A small retrospective study in Japan reported that dulaglutide 0.75 mg improved liver enzymes, glucose metabolism, and liver stiffness in patients with MASLD and T2DM after 12 weeks

However, none of these medications seem to induce as much weight loss as tirzepatide (Zepbound): People who take the maximum injectable dose of 15 mg weekly lose, on average, about 20 percent of their overall body weight in 72 weeks

doi: 10.1016/j.molmet.2017.11.009 32 YoungAAGedulinBRRinkTJ

[8] [9] Beyond pancreatic effects, these medications significantly slow gastric emptying, which prolongs the sensation of fullness after meals

Rybelsus says on its website that people on the medication in one clinical trial lost around eight pounds over a six-month period