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The Oasis program now counts four studies after a trial with a halved semaglutide dose for people with severe obesity has been added to the mix.

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Purpose of Review: This article summarizes the medical management of obesity with an emphasis on incretin-based therapeutics that target the neuro-hormonal basis of obesity.Recent Findings: Medications that mimic the effect of incretins, a group of peptide hormones released in response to nutrient intake that regulate appetite, result in potent and durable weight loss

In particular, noninvasive approaches are urgently required

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