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It also slows down digestion through delayed gastric emptying, which helps stabilize blood sugar regulation and prevents sharp spikes after meals

Ongoing research promises further novel applications, including neuroprotection and addiction

Consequently, IGFBPs regulate diverse cellular processes such as proliferation, adhesion, migration, survival, growth, apoptosis, senescence, autophagy, and angiogenesis through IGF-dependent and IGF-independent pathways [93, 101, 103]

10.1016/S0002-9440(10)63408-6 70 KharbandaK

Similar results were reported in mice treated with GLP-1/dexamethasone, an unimolecular peptide-nuclear hormone conjugate designed to optimize dexamethasone delivery into GLP-1R positive cells [820]