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Im not telling you to stop taking them

Transplantable rat glucagonomas cause acute onset of severe anorexia and adipsia despite highly elevated NPY mRNA levels in the hypothalamic arcuate nucleus

This same principle applies when comparing semaglutide, tirzepatide, and future medications such as retatrutide

Liraglutide: short-lived effect on gastric emptyinglong lasting effects on body weight

There is evidence to suggest that, as in the NST, CCK and estradiol also act synergistically in the limbic-hypothalamic circuit
