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Metformin is primarily used for lowering blood glucose levels in patients with type 2 diabetes mellitus, gestational diabetes, patients with prediabetes, and sometimes in women with polycystic ovary syndrome (PCOS) who have insulin resistance

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While broad-spectrum inhibitors (e.g., Batimastat) failed due to dose-limiting musculoskeletal toxicities, highly selective agents like Andecaliximab (targeting MMP-9) offer a more precise alternative

You need extra care if you are taking the following: Diabetes medicines Other GLP-1 receptor agonist Antidepressants Antibiotics Blood pressure tablets Blood thinners Herbal supplements But dont worry, many of these interactions can be safely managed if you undergo regular monitoring, change your doses, and get support from your healthcare team