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At a glance: Retatrutide (12 mg): 28.7% weight loss Tirzepatide (15 mg): 20.9% weight loss But this isnt a fair comparison

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Macrophages secrete proinflammatory cytokines, participate in the innate immune response, damage tissues, and function in the development of UC [29]

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Remember that semaglutide regulates appetite, making you more likely to end up in a calorie deficit

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If GI side effects persist beyond the adjustment period or are severe enough to significantly impact quality of life, dose adjustment may be warranted

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Prevention Tips Avoid very large meals Do not lie down immediately after eating Reduce spicy and fried foods Eat dinner early 6

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