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Thanks to Dr Ricardo Cohen Ricardo Cohen New England Journal of Medicine (NEJM) Semaglutide

In late 2025, a seemingly narrow advertising dispute told a much bigger story about the GLP-1 market

Most semaglutide users experience their first side effects within 24 to 48 hours of the initial injection, though timing varies by individual metabolism and dose escalation
Genetic predispositions in GLP-1 and GIPR pathways may help inform personalized treatment selection alongside clinical assessment

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