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Methods The study adhered to the ethical principles of the Declaration of Helsinki 33 and followed the Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) guideline

Serious side effects are possible including acute secondary angle closure glaucoma, decreased sweating and increased boy temperature, metabolic acidosis, suicidal ideation, kidney stones, and fetal toxicity

GLP-1 medications cause systemic fat reduction rather than targeted loss, meaning skin looseness can occur throughout the body rather than in isolated areas

It also reduces appetite and food intake via effects on the brain

Daily, custom days, cycling, titration ramps configure any protocol