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Description
In people with normal glucose tolerance, the early (30- or 60-minute) rise in plasma glucose following a 75 g oral glucose challenge is directly proportional to the rate of emptying, while this relationship is reversed at 120 minutes (the time point conventionally used in the diagnosis of diabetes)
Nausea is the most commonly reported early effect, followed by reduced appetite, mild stomach discomfort, and occasional vomiting in sensitive individuals

Heinrich L, Tissot N, Hartmann DJ, Cohen R

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Advertisement Because patients with type 2 diabetes are both deficient in and resistant to their own GLP-1 hormone, providing GLP-1 as a medication using high pharmacologic doses is considered to be a second-line treatment option for many patients
