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First, most studies have been conducted in male rodents, limiting the generalizability of findings to female subjects and precluding analysis of sex-dependent responses

Off-Label Use: A Growing Concern GLP-1s approved for T2D are frequently used off-label for weight loss, raising concerns among both employers and health plans

Additionally, rising awareness, coupled with broader access to treatment, is boosting more individuals to seek medical support for weight management, thereby strengthening growth in this segment

These key factors can slow progress: metabolismhow fast your body burns calories at rest whether you dose as directed or skip doses lack of consistent lifestyle changes like diet and exercise stopping because of side effects age having a lower starting weight, BMI, or waist circumference The Bottom Line Both liraglutide and semaglutide help control blood sugar, support weight loss, and lower cardiovascular risk