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Because people feel sick
Beyond these metabolic changes, cardiac fibroblasts in the HFpEF plus semaglutide condition display broad changes in ECM, ECM modifying enzymes, and ECM regulators
In that role, they help the body manage blood sugar more effectively, slow digestion, and increase satiety, which can lead to decreased appetite and food intake
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Inflammatory signals can alter hunger and fullness cues, making it harder to regulate appetite naturally
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