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In clinical trials, 89% of participants taking Zepbound at the 5mg dose achieved at least 5% body weight loss, while 96% of those taking the 10mg and 15mg doses reached this threshold

doi: 10.2337/db19-0324 35 CatalanoKJMadduxBASzaryJYoungrenJFGoldfineIDSchaufeleF
however, most of the studies accept the definition of WR as 10 kg of weight gain after reaching nadir weight

The conversion between semaglutide and tirzepatide is another option, as individual responses to each medication vary significantly
