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Description
The botanical product kratom produces opioid-like effects at high doses and is sometimes used for opioid replacement by individuals with opioid use disorder
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Common Adverse Events In clinical trials, the most frequently reported side effects were gastrointestinal: Nausea Diarrhea Vomiting Constipation Abdominal discomfort Decreased appetite[4][8][9] These symptoms were typically mild to moderate in severity and often occurred primarily during dose escalation phases[4][9]
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