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Hematocrit was measured at baseline, 24 weeks and 52 weeks
47 However, the number of events in these trials was relatively small compared with other trials in patients with HF
[139] conducted in vivo and in vitro experiments and found that the DNA methyltransferase inhibitor Zebularine can reduce the production of pro-inflammatory factors and improve brain edema and nerve function by increasing the expression of ZO-1 and vascular endothelial (VE)-cadherin [131, 132]
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