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Oral semaglutide was associated with direct cost increases of GBP 971 and GBP 963 versus empagliflozin 25 mg and sitagliptin 100 mg, respectively, over patient lifetimes, driven by the assumed higher acquisition cost of oral semaglutide and the differential times to treatment intensification, with patients receiving oral semaglutide for 1 additional year in the comparison with empagliflozin and for 2 additional years in the comparison with sitagliptin (Fig
A common fear is that tirzepatide loses effectiveness over time due to tolerance

%: percentage of participants in the full analysis set with at least one event

Since a significant proportion of people with obesity also have type 2 diabetes, the results may not fully reflect what would happen in that population

At 10mg/ml, even a small misread of the syringe changes your dose significantly