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Recent research suggests that high-concentration protein systems can leverage self-buffering to improve stability and patient comfort, potentially bypassing patents that require specific citrate or phosphate buffers

At the recommended starting dosage, one 20 mg vial will last approximately 840 weeks depending on the titration schedule

6,7,8,9,10 While tirzepatide produces greater weight loss than semaglutide in patients with T2D, 11 data from head-to-head trials comparing these therapies in patients with overweight or obesity are not yet available

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A: A patent can be challenged and invalidated through Paragraph IV litigation, inter partes review at the PTAB, or inequitable conduct findings