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Related Stories Semaglutide outperforms other GLP-1 drugs for weight loss in psychiatric populations Gum disease bacteria linked to calcific aortic valve stenosis Micro and nanoplastics in the blood linked to increased heart attack risk factors Longer duration of GLP-1RA use was associated with greater risk reduction

Therefore, the nutritionist represents together with the endocrinologist the key figures in the management of patients with PWS, since a close nutritional follow-up, adapted to the patient's life stages and in agreement with the caregivers is essential

When a synthetic GLP-1 agonist like semaglutide or tirzepatide activates these receptors, the effects ripple through multiple systems simultaneously

Application of liraglutide reduced mitochondrial damage by attenuating mitophagy via the protein phosphatase and tensin homolog-induced kinase 1 (PINK1)/Parkin pathway, the most well-known pathway for mitophagy (Figure 3)