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It is primarily intended for weight management in adults who are obese or overweight, especially those with related health conditions such as high blood pressure or type 2 diabetes

Muscle loss is another concern with all GLP-1 drugs

DPP-4 is an integral membrane protein which has a widespread distribution, being expressed in numerous tissues including intestinal and renal brush border membranes, vascular endothelium, the liver and pancreas, glandular epithelial cells, and by cells of the immune system (where it is also known as the T-cell differentiation antigen, CD26)