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[41] In addition, emerging therapeutic targets, such as peroxisome proliferator-activated receptors (PPAR-) agonists, AMPK activators, IRS modulators, and mTOR inhibitors, are currently being explored for their ability to restore metabolic homeostasis and prevent epileptogenic network formation

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Third, the 2-4% weight loss difference (if confirmed) may be statistically significant in studies but have little practical meaning for specific individuals
