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DPP-4 inhibitors raise incretin levels to normal or slightly above normal levels

This effect reduces appetite and supports weight loss, making them increasingly popular beyond diabetes treatment

The challenge is that when a patient stops taking their medication, the drug is gone but their food environment remains the same, said Dana Small, professor at McGill University and a Canada Excellence Research Chair in metabolism and the brain

The switch depends on your remaining beta cell function, current glucose control, overall health status, and treatment goals

As their use expands, questions naturally arise about potential side effects, including whether GLP-1 drugs cause blood clots