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Gastrointestinal adverse events in all treatment groups were more common among women than men, but rates of premature treatment discontinuation were similar for both genders

It is equally about industrial policy, regulatory cooperation and long-term pharmaceutical resilience."At the regional level, the African Continental Free Trade Area (AfCFTA) provides an opportunity to strengthen regulatory cooperation and coordinate procurement strategies, ultimately increasing Africa's collective bargaining power."The COVID-19 lesson that risks being forgottenThe COVID-19 pandemic was widely expected to reshape the relationship between intellectual property and public health.In October 2020, South Africa and India proposed a temporary waiver of certain TRIPS obligations covering vaccines, diagnostics and treatments, arguing that existing intellectual property rules could become a barrier to equitable access during a global health emergency.The negotiations that followed demonstrated just how difficult it remains to reconcile commercial interests with public health priorities

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More than four in five PwO have made a serious attempt at weight loss but less than half of them would have lost 5% of their body weight over three years, and 70% of those that do are expected to regain their losses.11 This illustrates that regardless of the drivers of obesity, PwO are in an established state of pathological energy homeostasis that requires intensification of treatment beyond foundational lifestyle changes, and which often requires the use of anti-obesity medications (AOMs)