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The highly-sought after drugs, sold under brand names like Wegovy, Ozempic, and Zepbound in the United States, were initially only recommended by WHO for the treatment of Type II diabetes in the EML
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Under stress conditions, BiP is released and thus activates the IRE-1, ATF6, and PERK signaling cascades

10.1016/j.neulet.2010.09.040 305

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