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Additionally, motor dysfunction in PD patients leads to reduced physical activity, further affecting energy consumption and metabolism ( 3.1 PD and insulin resistance Insulin resistance (IR) is usually considered a systemic response or reduced sensitivity to insulin effects

Third, medication use was based on prescription which may not reflect the real-use, and medication adherence was not considered in the present study

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GIP/GLP-1/GCGR, triple glucose-dependent insulinotropic polypeptide, glucagon-like peptide-1, and glucagon receptor agonist

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