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At week 52, both dulaglutide doses produced superior glycaemic control to sitagliptin, with mean HbA 1c reductions of 1.1% and 0.87% versus 0.39%, respectively (p.0.001 for both comparisons)

The procedure works best for patients with localized submental fat despite overall weight loss

GLP-1 agonists (semaglutide, tirzepatide) are the most expensive but also produce the most dramatic results, making the cost-per-pound-lost ratio competitive

Orforglipron (Foundayo) is a GLP-1 receptor agonist
