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Puzziferri N, Roshek TB, Mayo HG, Gallagher R, Belle SH, Livingston EH

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All participants in the oral-semaglutide group initiated oral semaglutide at 3 mg once daily

These findings suggest that GLP-1 medicines modulate inflammation through multiple pathways, including systemic metabolic improvements, direct actions on immune cells, and effects on non-immune cells that support interorgan communication of antiinflammatory signals (Figure 1 and Figure 2)

b represents reports with target drug exposure but without target AEs