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The study highlights compounding facilities that lack appropriate licenses to perform sterile compounding, as well as facilities that have faced recent disciplinary action

Although the abdomen may offer slightly faster uptake, this difference is not clinically significant when it comes to weekly dosing

However, clinical trials and real-world evidence consistently show that weight reduction with GLP-1RAs is accompanied by decrease in lean body mass, raising concern in patients already predisposed to muscle wasting and underscoring the need for integrated management strategies

Currently, access to Wegovy on the NHS remains limited due to supply constraints and eligibility criteria, and similar considerations may apply to Retatrutide initially