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[7] GLP-1 plays a huge part in metabolic health [8,9,10,11] Slowing digestion Promoting feelings of fullness (satiety) Reducing appetite Signaling insulin release Controlling blood sugar levels Preventing formation of new fat cells Stimulating fat burning (called thermogenesis) Maintaining desired body weight Bitters activate and increase GLP-1 to help deliver all of these metabolic benefits

The Lancet Diabetes & Endocrinology, 2025

What are you seeing among patients using GLP-1 weight loss medications

Pathological processes such as oligodendroglial insulin signaling defects, glial inflammation, mitochondrial stress, and impaired proteostasis overlap with pathways modulated by GLP-1R stimulation

Once you have reached the maintenance dose, you can continue to take the medication long-term
